Descrição:
William Morrow & Company. Used - Good. hardcover This item shows wear from consistent use but remains in good readable condition. It may have marks on or in it, and may show other signs of previous use or shelf wear. May have minor creases or signs of wear on dust jacket. Packed with care, shipped promptly.
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Adverse Reactions Capa dura - 1994
por Thomas Maeder
The author of Children of Psychiatrists recreates one of the largest and most controversial investigations in medical history, presenting the story behind Cholramphenicol, a widely-used antibiotic that resulted in hundreds of deaths, innumerable lawsuits, and countless FDA actions.
Descrição da contracapa
Miracle cure or lethal medicine? In 1949, chloramphenicol was hailed as the greatest drug since penicillin and proved amazingly effective against a host of previously untreatable deadly diseases. Marketed as Chloromycetin, it made its manufacturer, Parke-Davis, the largest pharmaceutical company in the world. But it was marred by a tragic flaw. Three years later, in 1952, Dr. Albe Watkins, a California general practitioner, inadvertently killed his own ten-year-old son with chloramphenicol. After learning that Parke-Davis already knew about other chloramphenicol-related deaths, Watkins embarked on an extraordinary cross-country pilgrimage that led the Food and Drug Administration to launch one of the largest investigations in medical history. Chloramphenicol saved too many lives to be taken off the market, but at the same time, it proved impossible to control. During three decades of FDA and American Medical Association warnings, half a dozen congressional hearings, and hundreds of lawsuits, doctors continued to prescribe the drug for trivial infections, needlessly killing more than a thousand people. In the 1980s, potentially lethal chloramphenicol residues were detected in U.S. dairy and beef cattle. In the 1990s, the FDA has found the drug in imported shrimp. How could this have happened? In seeking the answer to that question, Adverse Reactions provides a panoramic perspective over nearly half a century of the changing relationship among the pharmaceutical industry, the medical profession, the government, and patients, revealing how and why important decisions were made that affect us all today. To tell both sides of the story, Thomas Maeder has interviewed hundreds of people, fromthe man who dug up the sample of Venezuelan compost in which chloramphenicol was discovered, to the company scientists and executives who developed and marketed it, FDA officials who investigated and regulated it, families bereaved by it, lawyers who fought the issues in court, legislators who sought to control it, and physicians who both used and misused it. Adverse Reactions tells a gripping and profoundly disturbing story about the limits of corporate responsibility, government regulation, and medical knowledge.
Detalhes
- Título Adverse Reactions
- Autor Thomas Maeder
- Encadernação Capa dura
- Edição 1st Edition
- Páginas 480
- Volumes 1
- Idioma ENG
- Editorial William Morrow & Company, Scranton, Pennsylvania, U.S.A.
- Data de publicação 1994
- ISBN 9780688116828 / 0688116825
- Peso 1.85 libras (0.84 kg)
- Dimensão 9.57 x 6.44 x 1.43 in. (24.31 x 16.36 x 3.63 cm)
- Library of Congress subjects Chloramphenicol - History
- Número da Biblioteca do Congresso dos Estados Unidos 93031896
- Dewey Decimal Code 363.194
Revisões da mídia
Citações
- Kirkus Reviews, 02/15/1994, Page 203
- Library Journal, 03/15/1994, Page 96
- Publishers Weekly, 02/21/1994, Page 244
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Adverse Reactions
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Adverse Reactions
por Maeder, Thomas
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Frederick, Maryland, United States
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William Morrow & Company. Used - Very Good. Very Good condition. Very Good dust jacket. A copy that may have a few cosmetic defects. May also contain light spine creasing or a few markings such as an owner’s name, short gifter’s inscription or light stamp.
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Adverse Reactions
por Thomas Maeder
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Seattle, Washington, United States
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Descrição:
HarperCollins Publishers, 1994. Hardcover. Good. Disclaimer:A copy that has been read, but remains in clean condition. All pages are intact, and the cover is intact. The spine may show signs of wear. Pages can include limited notes and highlighting, and the copy can include previous owner inscriptions. An ex-library book and may have standard library stamps and/or stickers. At ThriftBooks, our motto is: Read More, Spend Less.Dust jacket quality is not guaranteed.
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Adverse Reactions
por Thomas Maeder
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Gilbertsville, Pennsylvania, United States
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Descrição:
Item Weight 1.82 poundsHardcover 480 pages
ISBN-10 0688116825
ISBN-13 978-0688116828
Dimensions 6.5 x 1.25 x 9.5 inches
Publisher William Morrow & Co; 1st edition (April 1, 1994)
Language: English
Hardcover. GOOD. Complete with very good dust jacket!
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Adverse Reactions
por Maeder, Thomas
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- first
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- 1st Edition
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Burgin, Kentucky, United States
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William Morrow & Co, Scranton, PA, 1994. 1st Edition. Hardcover. Very Good Condition/Very Good. 1st printing. Ex-library. Quantity Available: 1. ISBN: 0688116825. ISBN/EAN: 9780688116828. Pictures of this item not already displayed here available upon request. Inventory No: 1560716974. . 9780688116828
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Adverse Reactions
por Maeder, Thomas
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Vancouver, Washington, United States
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Scranton, Pennsylvania, U.S.A.: William Morrow & Co, 1994. Hardcover in near fine condition with near fine dust jacket.. Hardcover. Near Fine/Near Fine.
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Adverse Reactions
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Newport Coast, California, United States
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hardcover. Good. Access codes and supplements are not guaranteed with used items. May be an ex-library book.
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Adverse Reactions
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San Diego, California, United States
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William Morrow & Company. hardcover. New. New. In shrink wrap. Looks like an interesting title!
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Adverse Reactions
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Ferndale, New York, United States
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Scranton, Pennsylvania, U.S.A.: William Morrow & Co. New. 1994. Hardcover. 0688116825 .*** FREE UPGRADE to Courier/Priority Shipping Upon Request *** *** IN STOCK AND IMMEDIATELY AVAILABLE FOR SHIPMENT - FLAWLESS COPY, BRAND NEW, PRISTINE, NEVER OPENED -- with a bonus offer-- .
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