Platelet Proteomics: Principles, Analysis, and Applications (Wiley Series on Mass Spectrometry) Capa dura - 2011 - 1st Edição
por GARCIA
Descrição da contracapa
The groundbreaking new book that covers platelets, their role, and their study through proteomics research
Platelets are defined as small anucleate cells that circulate in the blood and play a fundamental role in haemostasis and thrombosis. From a pharmacological perspective, unwanted platelet activation forms blood clots and promotes cardiovascular disease--the leading cause of death in the Western world.
Platelet Proteomics focuses on the cutting-edge science in the emerging field of platelet proteomics research--a vital analytical method for the study of platelet activity. Written by a variety of contributors at the forefront of platelet research, this invaluable reference covers the recent developments in analyzing the proteome of basal and activating platelets in providing opportunities for advancing the discovery of new proteins that could eventually become drug targets for platelet-based illness. Features of this book include:
- Coverage of non-gel based separation methods (MudPit), analysis of the general platelet proteome and signaling cascades by gel-based separation methods (2-DE), and sub-proteome analyses (secretome/releasate, membrane proteins, organelles)
- A focus on the main research done on platelet proteomics, such as general proteome mapping, mapping signaling pathways, secretome and membrane proteomics, studies integrating other "-omics," and application to platelet-related diseases
- An examination of platelet-specific problems in a widely applicable fashion--the signaling proteome chapter serves as a model for investigations in many other cell types.
Covering key principles as well as the latest applications in proteome analyses, Platelet Proteomics makes a significant contribution to an area of study with exciting potential. This inaugural foray into platelet exploration is a blueprint for the future--and is expansive enough in scope to reach across many scientifi c disciplines.
Detalhes
- Título Platelet Proteomics: Principles, Analysis, and Applications (Wiley Series on Mass Spectrometry)
- Autor GARCIA
- Encadernação Capa dura
- Número da edição 1st
- Edição 1
- Páginas 403
- Idioma ENG
- Editorial Wiley
- Data de publicação 2011-05
- Features Bibliography, Index, Table of Contents
- ISBN 9780470463376
Revisões da mídia
Citações
- Reference and Research Bk News, 08/01/2011, Page 222
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