Nanochromatography and Nanocapillary Electrophoresis: Pharmaceutical and Environmental Analyses Capa dura - 2009 - 1st Edição

The latest tested and proven methods for detecting nanolevels of drugs and xenobiotics

Filling an important gap in the literature, this book enables you to successfully perform nanoanalyses using chip-based nanoliquid chromatography (NLC) and nanocapillary electrophoresis (NCE). The authors carefully guide readers through each stage of the instrumentation, detection, and applications of NLC and NCE in order to accurately identify compounds at a nanogram per liter or lower. This is the first book in the world describing NLC and NCE techniques in separation science.

Nanochromatography and Nanocapillary Electrophoresis begins with an introductory chapter that defines and sets forth a protocol for nanoanalyses. The chapters that follow guide you step by step through such important topics as:

• Fabrication of microchips

• Instrumentation, detection, and sample preparation in NLC and NCE

• Nano high-performance liquid chromatography

• Nanocapillary electrochromatography and nanomicellar electrokinetic chromatography

• Chiral separations by nanoliquid chromatography and nanocapillary electrophoresis

Throughout the book, the authors translate theory into practice, with examples of applications in materials science, nutrition, agriculture, chemistry, biology, and environmental science. Each chapter ends with a set of conclusions highlighting the most salient points as well as references to guide readers to the primary literature for further research.

This book equips readers with new, sophisticated tools to detect and analyze drugs and xenobiotics at nano levels. It is therefore highly recommended for scientists, researchers, academicians, and students in analytical chemistry, environmental monitoring, drugs analyses, and chromatography.